Diversify your API supply chain and forecast your future with Pfizer CentreOne.
- Regulatory confidence
- A timeline you can trust
- Secure supply
- 25% of our Kalamazoo site colleagues in dedicated quality roles
- Medicine reaching patients on time
From our world-renowned Kalamazoo, Michigan manufacturing site, we produce over 1 million kg of API per year and reliably supply some of the most difficult-to-produce cortico- and hormonal steroids, prostaglandins, and antibiotics.
From farm to factory, raw ingredient to API, we can secure a safer supply chain.
Let’s collaborate on your API today.
Pfizer CentreOne offers a comprehensive range of complex API compounds and intermediates for drug product developers and manufacturers.
One of the first corticosteroids developed using legacy Upjohn plant sterol technology, hydrocortisone is prescribed around 4 million times annually in the U.S. for a broad range of therapeutic indications.
Semi-synthesized from phytosterols, Progesterone’s API provides the foundation for a broad range of therapeutics related to women’s reproductive health, menopausal and post menopausal health and veterinary applications.
EnvieroTM progesterone offers drug developers access to Pfizer’s ground-breaking green chemistry. By eliminating metal catalysts and the bulk of the organic solvents, environmentally damaging waste emissions have been reduced by more than 70 percent, while maintaining the same therapeutic benefits as Classic Synthesis Progesterone.
* EnvieroTM progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.
An anticoagulant derived from porcine sources Heparin is prescribed to treat a variety of conditions where clotting can create serious complications.
In pharmaceutical application, dinoprost tromethamine is used to support the reproductive health of mammals. Epoprostenol sodium Prostaglandin, a powerful vasodilator, is used to treat pulmonary arterial hypertension.
An androgen and anabolic steroid, testosterones are used primarily to treat male hormone insufficiency due to a variety of causes.
Steroid Intermediates are a bridge to more complex steroids, where the user does not desire, or does not have the capacity to develop a fully back integrated supply-chain in house.
One of the most prescribed medications in the U.S., dexamethasone is used to treat acute respiratory distress syndrome (ARDS), various inflammatory conditions and is on the World Health Organization's List of Essential Medicines.