Dinoprost tromethamine and Epoprostenol sodium Prostaglandin hormones

Dinoprost tromethamine F2a and Epoprostenol sodium Prostaglandin hormone APIs from Pfizer CentreOne are found in a broad range of pharmaceutical and agriculture applications.

Reliable commercial supply

Manufactured in the U.S., Pfizer CentreOne has been reliably synthesizing and supplying commercial volumes of Dinoprost tromethamine and Epoprostenol sodium Prostaglandin hormones to leading veterinary and human pharma companies for decades.

The first total syntheses of prostaglandin F2α was reported in 1969 and achieved the Japan Prize in 1989. Dinoprost, the name given to prostaglandin when used as a pharmaceutical, is used to support human and animal health. Epoprostenol sodium, a powerful vasodilator, is commonly used to treat pulmonary arterial hypertension.

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Contact us for more information on Pfizer CentreOne
Dinoprost tromethamine and
Epoprostenol sodium Prostaglandin API
and related products

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Specifications

Chemical name Sort descending	CAS#	Compendial	Formula	Molar mass
Dinoprost tromethamine	Cas # - 38562-01-5	Compendial - USP, EP	Formula - C₂₀H₃₃O₅	Molar mass - 475.6 g/mol
Epoprostenol sodium	Cas # - 61849-14-7	Compendial - USP, TGA, EU and more	Formula - C₂₀H₃₁NaO₅	Molar mass - 374.4 g/mol

Why partner with Pfizer CentreOne for API supply?

Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.

We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.

Our track record is our strongest asset, and this means our customers can count on us for their critical API supply.

When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:

Reliable API supply at flexible commercial volumes
Industry-leading EHS and compliance track record
Advanced, efficient and environmentally friendly chemistries and processes
Regulatory support to enable your product’s success
Robust, low-risk internal supply chain from raw material to API
Transparent timelines and a responsive, dedicated customer support team
Drug product development and manufacturing services
Experienced teams backed by world-class Pfizer quality manufacturing systems – 25% of Kalamazoo colleagues are in dedicated quality roles
A track record you can trust

Related API products

Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.

Enviero Progesterone^* Heparin Hydrocortisone Progesterone Prostaglandins Steroid Intermediates Testosterone

* Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.

Let’s collaborate on your API today

To find out more about Pfizer CentreOne’s APIs and intermediates, as well commercial pricing and supply availability click here.

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