The first total syntheses of prostaglandin F2α was reported in 1969 and achieved the Japan Prize in 1989. Dinoprost, the name given to prostaglandin when used as a pharmaceutical, is used to support human and animal health. Epoprostenol sodium, a powerful vasodilator, is commonly used to treat pulmonary arterial hypertension.
Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.
We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.
Our track record is our strongest asset, and this means our customers can count on us for their critical API supply.
When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:
Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.
*Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.