Patented in 1936 and approved for medical use in 1941, hydrocortisone is on the World Health Organization's List of Essential Medicines. Available as a generic, hydrocortisone is prescribed more than 4 million times annually in the U.S.1 Hydrocortisone was one of the first corticosteroids using plant sterol technology developed by the legacy Upjohn Company, to make this important medication available to patients around the world


A range of chemistries and particle sizes

Hydrocortisones from Pfizer CentreOne are supplied in a number of chemistries and particle sizes for a broad range of pharmaceutical applications: 

  • Hydrocortisone USP
  • Hydrocortisone USP micronized
  • Hydrocortisone hemisuccinate USP monohydrate
  • Hydrocortisone acetate, USP micronized

Contact us for more information on Pfizer CentreOne hydrocortisone API and related products

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Chemical name Sort descending CAS# Compendial Formula Molar mass
Hydrocortisone acetate, micronized Cas # - 50-03-3 Compendial - USP, EP, Canada, JP and more
Formula -  


Molar mass - 404.5 g/mol
Hydrocortisone hemisuccinate USP monohydrate Cas # - 2203-97-6 Compendial - EP
Formula -  


Molar mass - 462.5 g/mol
Hydrocortisone USP Cas # - 50-23-7 Compendial - USP, EP, Canada, IP, JP and more
Formula -  


Molar mass - 362.4 g/mol
Hydrocortisone USP micronized Cas # - 50-23-7 Compendial - USP, EP, Canada, IP, JP and more
Formula -  


Molar mass - 362.4 g/mol

Why partner with Pfizer CentreOne for API supply? 

Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.

We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.

Our track record is our strongest asset, and this means our customers can count on us for their critical API supply. 

When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:

  • Reliable API supply at flexible commercial volumes
  • Industry-leading EHS and compliance track record
  • Advanced, efficient and environmentally friendly chemistries and processes
  • Regulatory support to enable your product’s success  
  • Robust, low-risk internal supply chain from raw material to API
  • Transparent timelines and a responsive, dedicated customer support team
  • Drug product development and manufacturing services
  • Experienced teams backed by world-class Pfizer quality manufacturing systems – 25% of Kalamazoo colleagues are in dedicated quality roles 
  • A track record you can trust

Related API products 

Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.

Enviero Progesterone*
Steroid Intermediates 

*Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.

Let’s collaborate on your API today

To find out more about Pfizer CentreOne’s API and intermediates, as well commercial pricing and supply availability click here.