Approved for medical use in 1941, hydrocortisone USP is used widely in topical treatments for inflammation and is on the World Health Organization's List of Essential Medicines. Prasterone, the most common steroid hormone found in humans, is a precursor for both androgens and oestrogens. Prasterone acetate, a key intermediate, is used in the commercial processing of select steroid based APIs. 

Available formulations

  • Prasterone acetate
  • Hydrocortisone USP

Contact us for more information on Pfizer CentreOne steroid intermediates, API and related products

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Chemical name Sort descending CAS# Compendial Formula Molar mass
Hydrocortisone USP Cas # - 50-23-7 Compendial - USP, EP, Canada, IP, JP and more
Formula -  

C21H30O5

Molar mass - 362.4 g/mol
Prasterone acetate Cas # - 853-23-6 Compendial - US DMF
Formula -  

C21H30O3

Molar mass - 330.4 g/mol

Why partner with Pfizer CentreOne for API supply? 

Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.

We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.

Our track record is our strongest asset, and this means our customers can count on us for their critical API supply. 

When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:

  • Reliable API supply at flexible commercial volumes
  • Industry-leading EHS and compliance track record
  • Advanced, efficient and environmentally friendly chemistries and processes
  • Regulatory support to enable your product’s success  
  • Robust, low-risk internal supply chain from raw material to API
  • Transparent timelines and a responsive, dedicated customer support team
  • Drug product development and manufacturing services
  • Experienced teams backed by world-class Pfizer quality manufacturing systems - 25% of Kalamazoo colleagues are in dedicated quality roles
  • A track record you can trust 

Related API products 

Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.

Dexamethasone
Enviero Progesterone*
Heparin 
Hydrocortisone
Progesterone 
Prostaglandins 
Testosterone

*Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.

Let’s collaborate on your API today

To find out more about Pfizer CentreOne’s API and intermediates, as well commercial pricing and supply availability click here.