First synthesized in 1957 and approved for medical use in 1961, dexamethasone is on the World Health Organization's List of Essential Medicines. Available as a generic, dexamethasone is one of the most prescribed medications in the U.S., with nearly 1.5 million prescriptions written by physicians in 20181.
Dexamethasone from Pfizer CentreOne is available in the following chemistries and particle sizes for a broad range of pharmaceutical applications:
For full information on Pfizer CentreOne dexamethasone APIs and related products
|Chemical name||CAS#||Compendial||Formula||Molar mass|
|Dexamethasone acetate anhydrous micronized||Cas # - 1177-87-3||Compendial - USP, Canada, UK, France and more||
|Molar mass - 452.5 g/mol|
|Dexamethasone sodium phosphate||Cas # - 2392-39-4||Compendial - US, Canada, EP, Singapore||
|Molar mass - 516.4 g/mol|
|Dexamethasone USP micronized||Cas # - 50-02-2||Compendial - USP, EP, JP, Canada and more||
|Molar mass - 392.4 g/mol|
Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.
We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.
Our track record is our strongest asset, and this means our customers can count on us for their critical API supply.
When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:
Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.
*Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.