Dexamethasone corticosteroids and corticosteroid esters

Dexamethasone corticosteroid APIs from Pfizer CentreOne are found in a variety of therapeutic formulations treating patients every day.

Reliable commercial supply

Manufactured in the U.S., Pfizer CentreOne has been reliably synthesizing and supplying commercial volumes of dexamethasone corticosteroid hormone APIs to leading pharma companies for decades.

First synthesized in 1957 and approved for medical use in 1961, dexamethasone is on the World Health Organization's List of Essential Medicines. Available as a generic, dexamethasone is one of the most prescribed medications in the U.S., with nearly 1.5 million prescriptions written by physicians in 20181.

https://clincalc.com/DrugStats/Drugs/Dexamethasone

A range of chemistries and particle sizes

Dexamethasone from Pfizer CentreOne is available in the following chemistries and particle sizes for a broad range of pharmaceutical applications:

Dexamethasone acetate anhydrous micronized
Dexamethasone sodium phosphate
Dexamethasone USP micronized

For full information on Pfizer CentreOne dexamethasone APIs and related products

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Pfizer CentreOne Dexamethasone API
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Specifications

Chemical name Sort descending	CAS#	Compendial	Formula	Molar mass
Dexamethasone acetate anhydrous micronized	Cas # - 1177-87-3	Compendial - USP, Canada, UK, France and more	Formula - C₂₄H₃₃FO₇	Molar mass - 452.5 g/mol
Dexamethasone sodium phosphate	Cas # - 2392-39-4	Compendial - US, Canada, EP, Singapore	Formula - C₂₂H₂₈FNa₂O₈P	Molar mass - 516.4 g/mol
Dexamethasone USP micronized	Cas # - 50-02-2	Compendial - USP, EP, JP, Canada and more	Formula - C₂₂H₂₉FO₅	Molar mass - 392.4 g/mol

Why partner with Pfizer CentreOne for API supply?

Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.

We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.

Our track record is our strongest asset, and this means our customers can count on us for their critical API supply.

When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:

Reliable API supply at flexible commercial volumes
Industry-leading EHS and compliance track record
Advanced, efficient and environmentally friendly chemistries and processes
Regulatory support to enable your product’s success
Robust, low-risk internal supply chain from raw material to API
Transparent timelines and a responsive, dedicated customer support team
Drug product development and manufacturing services
Experienced teams backed by world-class Pfizer quality manufacturing systems – 25% of Kalamazoo colleagues are in dedicated quality roles
A track record you can trust

Related API products

Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.

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^*Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.

Let’s collaborate on your API today

To find out more about Pfizer CentreOne’s APIs and intermediates, as well commercial pricing and supply availability click here.

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