Pfizer CentreOne Manufacturing Site in Grange Castle, Ireland

Intelligent collaboration with Pfizer CentreOne 

Pfizer’s global network allows access to commercial expertise in: 

  • Microbial fermentation
  • Mammalian cell culture
  • Viral cell culture
  • Vaccines
  • Cytotoxin production
  • Purification
  • Pegylation  

Partner with us to leverage our expertise in manufacturing biologics using expression in recombinant organisms including vaccine drug substances and intermediates, therapeutic proteins, and monoclonal antibodies (mAbs) and mAb biosimilars.

We leverage single-use technologies to deliver greater speed and efficiency, additional assurances of eliminating cross contamination, as well as simpler cleaning validation and process simplification.

Mastery in tech transfer, process optimization and scale-up

Our experts collaborate to explore ways of optimizing the manufacturing process. Our analytical, engineering, chemistry, and microbiological specialists are available to answer your questions and ensure your products are manufactured as efficiently as possible to the highest quality. 

Our robust tech transfer process maintains consistency and quality in commercial manufacturing. 

Integrated facilities

Leveraging Pfizer’s Global Manufacturing Network, we can deliver upstream and downstream drug substance manufacturing combined with sterile fill finish for drug  product at one location, with an integrated, scalable program. Our experts can partner with development teams to enable seamless integration across the lifecycle of your molecule, from development to commercial manufacture.  


  • Lyophilization of intermediates 
  • Raw material sourcing 
  • Cell bank storage 
  • Wave expansion 
  • GE Xcellerex XDR 2000 bioreactor 
  • Viral filtration
  • Tangential Flow Filtration (TFF) 
  • Chromatography 
  • Extractables and Leachables (E&L) studies 
  • Comprehensive sterile filling capabilities including lyophilization and pre-filled syringe