Insights & Resources | Pfizer CentreOne

Articles

The Importance of End-To-End Thinking During Drug Product Development - Outsourced Pharma

Throughout a drug product development program it is important to build robustness and flexibility into the manufacturing process. In this article, Dr. Kashif Ghaffar, process validation pharmacist at Pfizer's Freiburg manufacturing site, discusses what needs to be considered during product development in preparation for commercial manufacture.

Articles

Making the Medicine Go Down: Specialized Oral Solids Delivery Technologies - Outsourced Pharma

Most oral solids formulations are designed to release the drug immediately after swallowing for rapid absorption into the bloodstream. However, some products have been developed to release the drug in a specific way following ingestion and provide a "controlled-release" of the drug products. In this article, Sandra Conway, Technical Lead at Pfizer CentreOne, discusses some of the drug development technologies that provide a more specialized approach to oral dose delivery.

Articles

How To Select an API Partner for Strategic Success - Pharmaceutical Online

A strategic partner should always seek ways to innovate and improve your compound or product’s value, and do it with the dedication of a partner, not a supplier. With the growing importance of contract services and plenty of providers, it is more critical than ever to make the right choice. Where do you start? Tom Wilson, Pfizer CentreOne’s Contract Manufacturing Lead shares his tips for picking the perfect API partner.

Articles

Technical Considerations For Developing Oral Solids - Outsourced Pharma

Navigating your oral solids project from development through commercial manufacture can be a challenging path. In a two-part series, four oral solids experts from Pfizer CentreOne’s global network and partner organizations discuss the technical considerations to be aware of.

Articles

How Oral Solid Coating Technologies Can Enhance Delivery Strategy - Pharmaceutical Online

Oral solid dose (OSD) remains a dominant form in drug delivery and development and there are continual advances to improve oral solid stability, integrity, and robustness through technology platforms, including coating technologies. This article discusses the strategies and coating technologies that can aid complex OSD formulation.

Articles

An Easier Pill to Swallow - Pharma Manufacturing

The increasing complexity of molecules in the drug pipeline is bringing greater challenges in formulation and scale-up. OSD manufacturers must be armed with a breadth of technology and expertise from a multidisciplinary team. Kieran Coffey and Sandra Conway discuss strategies and coating technologies that can aid complex OSD formulation.

Articles

Cultivating an Efficient Scale-Up Strategy - Pharmaceutical Outsourcing

Developing drugs and preparing them for commercial markets is a challenging task. But as pharmaceutical companies manage manufacturing footprints and capital budgets, securing experienced manufacturing partners has become a priority. Drug development is evolving to treat chronic conditions and potent APIs are playing a central role. Many of these new treatments, including a long list of drugs in development, have very sophisticated chemistries. Not only are these compounds tough to formulate in the lab, their chemistries become more challenging to synthesize and scale in commercial volumes. Early formulation of API chemistry is key for efficient scale-up. Offering insights gleaned from successfully scaling hundreds of API programs, Pfizer CentreOne’s Justin Divan discusses API scaling challenges and advises on best practices and offers his insight.

Articles

Greener by Design - Contract Pharma

The reasons to adopt green chemistry are many and varied. Whatever the reason, it is likely green chemistry principles are being applied to facilitate process change—wherever it may come from. Green chemistry just makes sense, economically, for the environment, and especially for safety. Read more in the article by Kenneth Ball.

Articles

Contract Manufacturing Roundtable - European Pharmaceutical Manufacturing

Contract manufacturers, like Pfizer CentreOne, serve as reliable partners for their customers, offering expertise that is not available in-house to guide a drug securely and efficiently from development to commercial manufacture. Our VP, global contract manufacturing leader, Tom Wilson, joined a group of industry leaders to discuss this sector's changing landscape.

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Tom Wilson discusses better drug manufacturing strategies with Contract Pharma

Contract Pharma sat down with Tom Wilson, VP, Global Contract Manufacturing Lead at Pfizer CentreOne, to discuss how today’s biopharma companies are turning to their contractors for long-term collaboration and support.

Articles

Pfizer CentreOne's JoyL Silva comments on the evolution of outsourcing in the pharmaceutical industry with Contract Pharma

Contract Pharma sat down with Pfizer CentreOnes’ general manager, JoyL Silva, and other industry leaders to consider how business operations have evolved to accommodate changing industry need and what we can expect for the future of the industry and outsourcing.

Articles

JoyL Silva on the benefits of the embedded CDMO model with European Pharmaceutical Manufacturing

The European Pharmaceutical Manufacturer sat down with JoyL Silva, former General Manager of Pfizer CentreOne, to discuss the benefits an embedded CDMO model brings and how Pfizer CentreOne operates within one of the world’s premier biopharmaceutical companies.