Pfizer CentreOne Manufacturing Site in Kalamazoo, United States

Intelligent collaboration with Pfizer CentreOne

You can rely on us for high-quality small molecule API manufacturing. Our commercial manufacturing capabilities span Pfizer’s global small molecule portfolio, and we put those resources to work for you. 

Our Kalamazoo, Michigan facility serves your small molecule API manufacturing needs, with decades of experience and more than one million kilograms of APIs manufactured every year. Located in the heart of the United States, the site produces APIs and intermediates using Pfizer quality standards – the same that Pfizer uses for its own branded medicines. 

Pilot cGMP manufacturing

With the flexibility to support small clinical or commercial batches as well as scale to commercial volumes, our cGMP pilot facilities can grow with your API demand. 

Our team of analytical chemists and engineers are experts at developing and trouble-shooting analytical methods and scaling your process successfully. We collaborate with you to redesign and optimize chemical processes wherever possible. Analytical, engineering and chemistry teams aim to reduce risk so we can manufacture your products reliably at a large scale, as efficiently as possible. 

Let's collaborate

Henry Browning, Process and Product Technology, United States

Compound Types

  • Most small molecules excluding cytotoxics and betalactams


Batch Sizes

  • From 100 grams to 3+ metric tons


  • Complex organic synthesis 
  • Fermentation and bioprocessing up to 150,000-liter scale with several isolation technologies
  • Milling and micronizing
  • Process optimization and scale up
  • Process industrialization
  • Particle sizing 
  • Containment and segregation 
  • Steroids, hormones and prostaglandins 
  • Controlled substances
  • OEB 1-3