Your trusted CDMO partner of choice

When it comes to high-quality small molecule manufacturing, we always deliver on what we promise. Our commercial manufacturing capabilities span Pfizer’s global small molecule portfolio, and we’ve packaged this up into services that work for you.

We serve your small molecule API needs from our Kalamazoo, Michigan facility, bringing decades of experience and manufacturing more than 1 million kg of APIs every year. Located in the heart of the United States, the site produces APIs and intermediates using Pfizer quality standards – the same that Pfizer uses for its own branded medicines.

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Pilot cGMP manufacturing

With the flexibility to support small clinical or commercial batches, as well as scaling to commercial volumes, our cGMP pilot facilities can grow with your API demand. This means we are dedicated to your long-term success.

Our team of analytical chemists and engineers are experts at developing and trouble-shooting analytical methods and scaling your process successfully. We collaborate with you to redesign and optimize chemical processes wherever possible. Analytical, engineering and chemistry teams aim to reduce risk so we can confidently scale to fit your unique manufacturing needs.

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Small molecule API manufacturing capabilities at a glance

Compound types

  • Most small molecules excluding cytotoxics and betalactams
  • From 100 grams to 3+ metric tons


  • Organic synthesis
  • Fermentation and bioprocessing up to 150,000-liter scale
  • Particle sizing Process optimization and scale-up from lab to commercial
  • Containment and segregation
  • Highly potent, steroids, hormones and prostaglandins
  • Controlled substances CII, CIII OEL <1 µg/m³ and 1-10 µg/m³
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Expert content

Read about our small molecule API capabilities that we offer

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Expert Content Including Quality Attributes for Strategic Small Molecule API Partners

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Explore our global small molecule API manufacturing capabilities

Kalamazoo Site


Kalamazoo, Michigan, USA

  • The largest manufacturing site in the Pfizer network
  • Produces approximately 1 million kg of API and 10 million kg of intermediates every year
  • Manufactures antibiotics, hormones and vaccines as well as rare disease and oncology treatment
  • Designated a National Chemical Historic Landmark by the American Chemical Society

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