Resources

Search

Menu

Close

Resources

Contact us

Manufacturing services

Oral solid dose

Sterile injectables

Antibody-drug conjugates

Tech transfer

Manufacturing network

OSD manufacturing

SI manufacturing

ADC manufacturing

About us

Careers

Leadership team

Sustainability

IP protection

Expert insights

ADC Manufacturing

Antibody-drug conjugate excellence from Pearl River and North Creek


Pfizer CentreOne helps deliver confidence in every conjugate through two extensive facilities dedicated to antibody-drug conjugate manufacturing. At North Creek, WA, 51,000 square feet of purpose-built space enables mammalian antibody and ADC manufacturing with advanced single-use technologies and a highly skilled team. Leveraging approximately 24,000 square feet of ADC manufacturing space specifically designed for highly potent and cytotoxic drug processing, the Pearl River, NY, site empowers you to bring life-changing ADC therapies to patients faster.

Download brochure

Loading

Pearl River's capabilities at a glance

  • Cytotoxic compounds and drug substance intermediates
  • Mammalian cell culture and purification with single-use technologies
  • Small-scale bacterial fermentation, recovery, and purification
  • Single-use ADC conjugation facility processing up to 2kg antibody scale
  • Conjugation reactions, chromatography, diafiltration, and formulation for bioconjugate development
  • Small molecule chemistry capabilities for diverse therapeutic applications
  • High-value formulations in a wide range of batch sizes
  • The entire product flow path is single-use
  • In-house QC labs for in-process, release and stability testing

Time is life

Our global network of scientists, regulatory experts, and analytical  and quality control engineers is dedicated to streamlining your ADC’s path to market. 

 

By optimizing processes and leveraging our expertise, we reduce wait times for manufacturing suite access, accelerate process scale-up and minimize process cycle times, helping to ensure efficient and timely delivery of your life-changing therapy.

Explore our sites

Pearl River, NY

  • Small scale bacterial fermentation
  • Recovery
  • Chemical synthesis
  • Conjugation reactions
  • Purification
  • Formulation
  • Bulk liquid freezing/thawing
LoadingLoading

1/2

North Creek, WA

  • Built in 2015
  • 100+ manufacturing and support colleagues
  • Supplies to global markets
  • Sensitech Temp Tales for waste elimination
  • Clinical and commercial cGMP manufacturing
  • Received the 2021 Gold Award and 2022 Silver Award from the King County Department of Natural Resources and Parks Industrial Waste Program
LoadingLoading

2/2

Loading

Success

Thank you, your submission has been received!

A CMO for therapies that define legacies

Follow us

Latest marketing updates 

Sign up

Loading

© 2025 Pfizer Inc. All rights reserved. Pfizer CentreOne is a registered trademark of Pfizer Inc. Privacy Policy | Terms of Use