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Microbial therapeutic legacies, powered by Pfizer

From fermentation to long-term supply continuity, your microbial therapies face complex challenges.

At Pfizer CentreOne, we help you overcome those hurdles with the resilience and precision delivered through the strength of Pfizer’s global network.

With microbial fermentation capacity across Pfizer’s Andover and Strängnäs sites, we combine extensive scientific depth, commercial-scale infrastructure and regulatory expertise to help bring your therapy to the patients waiting. 

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Why do microbial therapy innovators 
choose Pfizer CentreOne?

Powered by Pfizer, we leverage Pfizer’s global facilities with advanced capabilities to provide you with
the specialized expertise and agile solutions needed to help accelerate therapeutic breakthroughs.

Guiding you with extensive manufacturing expertise

  • Pfizer teams with complementary strengths in plasmid DNA, recombinant proteins, enzymes and vaccines
  • Decades of microbial fermentation and purification experience across global facilities
  • Experience with complex microbial systems, including BSL-2 organisms and advanced feed/media strategies
  • A track record supporting licensed commercial products worldwide

A microbial network built to meet your needs

  • Late-stage clinical and commercial drug substance (DS) production
  • Flexible microbial manufacturing capacity up to 4000 L
  • Facilities designed for multiproduct operations
  • Dedicated microbial cell bank manufacturing and storage facilities
  • Comprehensive downstream capabilities, including centrifugation, automated lysis, UF/DF, chromatography and formulation 
  • Parallel fermentation trains and automated downstream processing available

Quality and reliability in every step

  • GMP-compliant clinical and commercial manufacturing and ISO-classified suites available across the network
  • Right-first-time approach supported by advanced automation and digital monitoring
  • Global Pfizer quality systems aligned with FDA, EMA, MPA, ANVISA and more
  • Dedicated QC and analytical labs supporting release, stability and regulatory compliance framework
  • Transparent ways of working with real-time data sharing and a strong compliance framework

Microbial therapeutics manufacturing

Across the globe, Pfizer offers microbial fermentation capabilities embedded within world-class manufacturing sites. 

With facilities built to scale, engineered for precision and run by scientific experts, we help you accelerate your microbial therapy to patients, because time is life.

Helping deliver microbial excellence
on a global scale

Strängnäs, Sweden

  • Scalable microbial fermentation up to 4,000 L
  • Integrated drug substance manufacturing on a single site
  • Designed for multi-product flexibility
  • Supplying global commercial programs
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Andover, Massachusetts

  • Microbial fermentation and downstream processing
  • Integrated downstream processing and QC testing
  • Multi-product GMP suites for clinical and commercial supply
  • Deep expertise in plasmid DNA and complex microbial systems
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