Enviero® progesterone from Pfizer CentreOne offers drug developers access to Pfizer CentreOne’s first product from our ground-breaking green chemistry, the same proprietary process we use to make APIs for our own products.
Enviero’s green chemistry represents a step-change in progesterone processing efficiency and sustainability. By eliminating metal catalysts and the majority of the organic solvents, environmentally damaging waste emissions have been reduced by more than 70 percent.
Offering a more resource and energy friendly approach to the process than initially developed in the 1940s, Enviero progesterone is manufactured in the U.S. via a proven biocatalytic process based on plant phytosterols and authorized for pharmaceutical use in North America and the European Union.
Using advanced chemistry developed over a decade, Enviero progesterone is the first API launched from Pfizer CentreOne’s green chemistry program. More than 500 metric tons of Enviero progesterone have been manufactured to date, with products containing the API now marketed in the U.S., Austria, Italy, Germany and France.
Enviero progesterone from Pfizer CentreOne is available in particle sizes for a broad range of pharmaceutical applications:
| Chemical name Sort descending | CAS# | Compendial | Formula | Molar mass |
|---|---|---|---|---|
| Enviero® progesterone micronized | Cas # - 57-83-0 | Compendial - CEP Granted, Filed with USFDA |
Formula -
C21H30O2 |
Molar mass - 314.4 g/mol |
| Enviero® progesterone micronized for soft gel | Cas # - 57-83-0 | Compendial - CEP Granted, Filed with USFDA |
Formula -
C21H30O2 |
Molar mass - 314.4 g/mol |
| Enviero® progesterone USP | Cas # - 57-83-0 | Compendial - CEP Granted, Filed with USFDA |
Formula -
C21H30O2 |
Molar mass - 314.4 g/mol |
Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.
We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.
Our track record is our strongest asset, and this means our customers can count on us for their critical API supply.
When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:
Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.
Dexamethasone
Heparin
Hydrocortisone
Progesterone
Prostaglandins
Steroid Intermediates
Testosterone
To find out more about Pfizer CentreOne’s API and intermediates, as well commercial pricing and supply availability click here.
