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Pfizer CentreOne has been a leading provider of specialty APIs for more than 50 years.

We make a specific segment of complex compounds:

  • Cortico- and hormonal steroids

  • Prostaglandins

  • Antibiotics

Our Kalamazoo, Michigan facility, located in the heart of the United States, produces APIs and intermediates that Pfizer uses for its own branded medicines. Pfizer pioneered the chemistry used to make complex steroids and hormones and continues to lead the industry by investing in next-generation processes. Look to us as an API supplier you can count on for quality and expertise.

To order, contact us, or call +1-269-833-2296

Our APIs & Intermediates

Chemical name CAS # Compendial API or Intermediate
12-PT 56188-04-6 USP Intermediate
16α-hydroxyprednisolone 13951-70-7 US and Canada DMF Intermediate
21-(acetyloxy) tetraene (3-TR) 37413-91-5 US DMF Intermediate
Betamethasone (11-DB) 981-34-0 US DMF Intermediate
Betamethasone 11 low bromo 981-34-0 US DMF Intermediate
Dexamethasone-8 (8DM) 24916-90-3 US DMF API
Dexamethasone acetate anhydrous micronized 1177-87-3 USP, Canada, UK, France and more API
Dexamethasone sodium phosphate 2392-39-4 US, Canada, EP, Singapore API
Dexamethasone USP micronized 50-02-2 USP, EP, JP, Canada and more API
Diketo acid 1944-63-4 95-100% Intermediate
Dinoprost tromethamine 38562-01-5 USP, EP API
Epoprostenol sodium 61849-14-7 USP, TGA, EU and more API
Hydrocortisone acetate 50-03-3 USP, EP, Canada, JP and more API
Hydrocortisone hemisuccinate USP monohydrate 2203-97-6 EP API
Hydrocortisone USP 50-23-7 USP, EP, Canada, IP, JP and more Intermediate & API
Hydrocortisone USP micronized 50-23-7 USP, EP, Canada, IP, JP and more API
Medroxyprogesterone acetate (2-MPB) Mixture Custom Intermediate
Megestrol acetate USP 595-33-5 USP, EP, Canada API
Megestrol acetate USP micronized 595-33-5 USP, EP, Canada API
Methylprednisolone USP 83-43-2 USP, EP API
Myristyl-gamma-picolinium chloride 2748-88-1 Custom n/a
Neomycin sulfate 100 mesh 1405-10-3 USP, EP, Canada, IP, JP and more API
Neomycin sulfate micronized 1405-10-3 USP, EP, Canada, IP, JP and more API
Neomycin sulfate USP 1405-10-3 USP, EP, Canada, IP, JP and more API
Nicergoline* 27848-84-6 France, Italy, Poland API
Novobiocin sodium 1476-53-5 USP API
Porcine heparin sodium USP 9005-49-6 USP, Canada API
Prasterone acetate 853-23-6 US DMF Intermediate & API
progEnviero progesterone micronized 57-83-0 Filed with USFDA and EDQM API
progEnviero progesterone micronized for soft gel 57-83-0 Filed with USFDA and EDQM API
progEnviero progesterone USP 57-83-0 Filed with USFDA and EDQM API
progEnviero progesterone USP special micronized 57-83-0 Filed with USFDA and EDQM API
Progesterone wettable powder 57-83-0 US, EP, Canada, IP and more API
Testosterone micronized 58-22-0 US, EP, Canada API
Testosterone USP 58-22-0 US, EP, Canada API
Testosterone cypionate 58-20-8 US API
Testosterone propionate micronized 57-85-2 US API
Testosterone undecanoate 5949-44-0 US, Europe, Canada API

*Nicergoline manufactured by third-party supplier under Pfizer supervision using Pifzer’s process API Terms and Conditions

Download our APIs & Intermediates brochure.

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Technical & Regulatory Support

You need a quick response when regulators call. That’s exactly what we provide you.

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Need scale-up and manufacture of your proprietary molecule instead?

That’s one of our core competencies.

See Custom APIs

Quality and Security of Supply

Fully backward integrated, we make your API “from scratch” in Pfizer’s Kalamazoo, Michigan, U.S.A., facility.

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Environmental Sustainability

Pfizer is finding ways to minimize our impact on the environment during the manufacturing of pharmaceuticals.

At our Kalamazoo site, from 2015 to 2018 we’ve implemented projects that have:

  • Reduced greenhouse gas emissions by 24,000 metric tons per year

  • Reduced hazardous waste disposal volume by 10 million kilograms per year

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Enviero™ Green-Chemistry Progesterone

Enviero (en-VI-ro) progesterone is the first compound to be launched from Pfizer CentreOne’s green-chemistry program:

  • More than 70% reduction in carbon footprint versus our traditional process

  • No metal catalysts

Learn more